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Ethyl Salicylate

Also known as ethyl 2-hydroxybenzoate, Sal ethyl, Mesotol, Salicylic ether

Ethyl Salicylate, also known as ethyl 2-hydroxybenzoate, is an aromatic ester with the molecular formula C9H10O3 and molecular weight 166.17. It is valued for its characteristic wintergreen-like odor and use as a fragrance and flavor ingredient where the suitability of the specific commercial grade has been established.

Aromatic Esters Salicylate Esters
C₉H₁₀O₃
C₉H₁₀O₃

Product identity

CAS number
118-61-6
Molecular formula
C9H10O3
Molecular weight
166.17 g/mol
Category
Aromatic Esters
Subcategory
Salicylate Esters
Common aliases
ethyl 2-hydroxybenzoate, Sal ethyl, Mesotol

Product overview

What is Ethyl Salicylate?

Ethyl Salicylate, also called ethyl 2-hydroxybenzoate, is an aromatic salicylate ester with CAS number 118-61-6. Its molecular formula is C9H10O3 and its stated molecular weight is 166.17. The molecule contains an ester group attached to a benzene ring bearing a hydroxyl substituent, giving it the structural features associated with salicylate chemistry. Additional names include Sal ethyl, Mesotol, Salicylic ether and Salotan.

As an organic aromatic ester, Ethyl Salicylate is commonly considered a scent-active and flavor-related material, with a characteristic sweet, balsamic, wintergreen-like sensory profile often described in formulation contexts. Its aromatic ring and ester functionality influence solubility, compatibility and reactivity. Behaviour can vary with concentration, solvent system, temperature and surrounding ingredients, so practical observations should be established in the intended formulation rather than assumed from identity alone.

Ethyl Salicylate is encountered in fragrance and flavor development, personal-care formulation, chemical synthesis and laboratory research. It may serve as a sensory ingredient, a composition component or a reference material in appropriate technical work. A common industry use does not automatically establish suitability for every product type, market or end use; formulators should assess the relevant grade, formulation requirements and applicable local rules before adoption.

Selection should begin with the intended function, concentration, route of incorporation and compatibility with the surrounding formulation. Attention may be needed for odour impact, taste considerations, volatility, solubility, colour, stability and interactions with other ingredients. Buyers should also define documentation, analytical testing and jurisdictional requirements appropriate to their application. Ethyl Salicylate should be evaluated as a specific material for a specific purpose, not treated as interchangeable with every salicylate ester.

Technical profile

Product properties

Review the product identity and general physical profile before specifying the grade required for your operation.

IUPAC name
ethyl 2-hydroxybenzoate
Category
Aromatic Esters
Subcategory
Salicylate Esters
Molecular formula
C9H10O3
Molecular weight
166.17 g/mol

Uses and markets

Applications and industries

The correct product specification depends on the intended process, grade requirements and operating conditions.

Detailed product information

Detailed Ethyl Salicylate product information

Composition and aromatic ester identity

Ethyl Salicylate is an aromatic ester formed from salicylic-acid-derived structure and an ethyl ester group. Its hydroxyl and ester functionalities contribute to the compound’s distinctive chemical behaviour, while the aromatic ring supports its recognizable sensory character. The material is identified by CAS 118-61-6 and molecular formula C9H10O3, making it straightforward to distinguish from related methyl, propyl or other salicylate esters.

The molecular structure matters when selecting solvents, preparing blends or comparing related ingredients. Although structurally similar salicylates may share broad sensory or formulation roles, differences in molecular size and functionality can affect odour profile, solubility, volatility and performance. Technical teams should therefore evaluate Ethyl Salicylate under actual use conditions rather than assuming that data for another salicylate transfers directly.

Formulation and development considerations

In fragrance, personal-care and selected flavor-related work, Ethyl Salicylate may contribute a sweet, balsamic or wintergreen-like note. Its impact depends strongly on dosage, blend composition and the surrounding medium. Sensory evaluation should be performed by suitably qualified personnel, especially when the material is combined with other aroma chemicals, solvents, oils or functional ingredients.

For development work, useful assessment points include compatibility, clarity, odour stability, colour change, incorporation method and behaviour during storage. The selected material should be reviewed against the finished product’s intended market and technical requirements. A compound’s recognized use in one formulation does not by itself establish suitability for another, particularly where exposure, labelling or local regulatory expectations differ.

Chemical synthesis and laboratory use

Ethyl Salicylate can be relevant to organic chemistry studies involving aromatic esters, hydroxyl-substituted benzoates and related transformations. It may be examined as a reaction substrate, comparison compound or formulation component in research and development. The appropriate role depends on the reaction scheme, solvent environment, catalysts, temperature and the analytical method used to follow the work.

Laboratories may also use the compound for identity checks, method development, reference comparisons or investigations of physical and sensory behaviour. Experimental planning should account for the compound’s functional groups and possible interactions with reagents. Any reaction-specific hazards, waste requirements and process controls should be established from the complete procedure and applicable workplace guidance rather than inferred from the product name alone.

Choosing material for intended use

A sound selection process links the material to a defined function, such as sensory contribution, analytical comparison or synthetic use. Review expected concentration, solvent compatibility, stability, odour influence and interactions with packaging or adjacent ingredients. Where the material enters a consumer-facing formulation, teams should separately assess finished-product requirements, jurisdictional obligations and any necessary toxicological or safety review.

Documentation should match the decision being made. Depending on the project, this may include identity information, analytical results, handling guidance, composition details and application-specific testing. Because performance depends on formulation and process conditions, small-scale trials and controlled evaluation are prudent before wider technical adoption. Ethyl Salicylate should be selected on demonstrated fit, not on name similarity alone.

Frequently asked questions

Questions about Ethyl Salicylate

Why does material specification matter when evaluating Ethyl Salicylate?

Chemical identity confirms that the material is Ethyl Salicylate, but it does not by itself define purity, physical form, concentration, test methods or suitability for a particular process. Those details belong to the current supplier specification and related documentation. Technical and purchasing teams should compare that information with the intended formulation, operating conditions and internal approval criteria before use. If the supplier, grade, process or end-use requirement changes, the earlier assessment may no longer apply. Keeping identity and specification separate helps prevent similarly named or differently supplied materials from being treated as automatically interchangeable. It also creates a clearer record for receiving, quality review and later change control.

How does the structure of Ethyl Salicylate influence its behaviour?

Ethyl Salicylate contains an aromatic ring, a hydroxyl group and an ester group. The aromatic portion contributes to its characteristic scent profile, while the ester functionality influences polarity, compatibility and chemical reactivity. The hydroxyl and ester groups can also affect interactions with solvents and neighbouring molecules. These structural features help explain why the compound behaves differently from hydrocarbons and from salicylates with different ester groups. Actual solubility, stability, odour strength and incorporation behaviour depend on concentration, temperature, solvent choice and formulation environment. Consequently, structure provides useful guidance, but practical testing remains important for a specific process or finished composition.

How does Ethyl Salicylate differ from Methyl Salicylate?

Both compounds are salicylate esters and share an aromatic ring with hydroxyl and ester functionality, but their ester groups differ. Ethyl Salicylate contains an ethyl group, whereas Methyl Salicylate contains a methyl group. That change affects molecular weight and can influence volatility, odour balance, solubility, sensory intensity and formulation behaviour. They should not be treated as automatically interchangeable, even when their broad application areas overlap. A substitution requires review of the intended function, dosage, sensory profile, analytical identity, finished-product requirements and applicable rules. Comparative trials are the appropriate way to determine whether one material can meet a particular formulation objective.

What should formulators evaluate before using Ethyl Salicylate?

Formulators should first define the intended function and the concentration range being considered. Important evaluation points can include odour contribution, taste implications where relevant, solvent compatibility, clarity, colour, stability, interaction with other ingredients and behaviour during processing or storage. The complete product context also matters: intended market, exposure pattern, labelling expectations and any required safety or regulatory review should be considered separately from the chemical identity. Small-scale compatibility and sensory trials can reveal effects that are not predictable from the name alone. The selected material should be supported by suitable technical documentation and assessed by personnel familiar with the target formulation.

Can Ethyl Salicylate participate in chemical reactions?

Yes. Ethyl Salicylate contains both an ester group and a phenolic hydroxyl group, so it can participate in reactions that are relevant to those functional groups under suitable conditions. The exact outcome depends on reagents, catalysts, solvent, temperature, concentration, water content and reaction time. It may therefore be used as a substrate, comparison compound or intermediate-related material in selected organic chemistry work. Reaction planning should be based on the complete procedure, including anticipated by-products, heat release, incompatibilities, analytical monitoring and waste treatment. No single reaction behaviour should be assumed for every process, and laboratory controls should follow the specific method.

What is the role of Ethyl Salicylate in analytical and research work?

In analytical and research settings, Ethyl Salicylate may serve as an identified compound for method development, comparison, formulation studies or investigations of aromatic ester behaviour. Researchers can examine its response in an analytical method, its compatibility with selected solvents, or its sensory and physical contribution to a test formulation. The appropriate purpose depends on the study design and the required measurement quality. Laboratories should define the identity, concentration, preparation method, instrument conditions and acceptance criteria relevant to their work. Results should be interpreted within the method’s limitations, because observations from one solvent system, instrument or formulation may not transfer directly to another.

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