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2-Propanone, hydrazone

Also known as propan-2-ylidenehydrazine, Acetone hydrazone, aceh, Isopropylidene hydrazine

2-Propanone, hydrazone, also called acetone hydrazone, is an organic hydrazone with formula C3H8N2 and molecular weight 72.11. Miilex Chemicals presents this compound for qualified worldwide customers evaluating synthetic, analytical and research uses.

Organic nitrogen compounds Ketone hydrazones
C₃H₈N₂
C₃H₈N₂

Product identity

CAS number
5281-20-9
Molecular formula
C3H8N2
Molecular weight
72.11 g/mol
Category
Organic nitrogen compounds
Subcategory
Ketone hydrazones
Common aliases
propan-2-ylidenehydrazine, Acetone hydrazone, aceh

Product overview

What is 2-Propanone, hydrazone?

2-Propanone, hydrazone is an organic nitrogen compound formed from propanone and hydrazine through condensation at the ketone carbonyl group. Its systematic name is propan-2-ylidenehydrazine, and it is also known as acetone hydrazone, isopropylidene hydrazine, or aceh. The molecular formula is C3H8N2, corresponding to a stated molecular weight of 72.11 and a structure containing a carbon–nitrogen double bond.

As a hydrazone, 2-Propanone, hydrazone combines a carbonyl-derived imine linkage with an amino nitrogen that can influence polarity and chemical reactivity. Its behaviour depends on solvent, acidity, water content, temperature, and the surrounding reaction system. Hydrazones can undergo hydrolysis under suitable conditions and may participate in further transformations through their nitrogen functionality, so handling and use should follow an appropriate assessment.

2-Propanone, hydrazone is principally encountered as a defined intermediate or model compound in organic synthesis, reaction studies, and analytical investigations. Its value comes from converting the reactivity pattern of propanone into a nitrogen-containing derivative that can be examined or carried forward. A common laboratory use does not by itself establish suitability for food, pharmaceutical, agricultural, or other regulated applications.

Selection should begin with the intended transformation, solvent system, water sensitivity, acidity, and the analytical method used to confirm identity or conversion. Buyers should compare 2-Propanone, hydrazone with related ketone hydrazones when steric effects, volatility, or downstream reactivity matter. The stated identity applies to this named compound; application suitability remains dependent on the specific formulation, process design, and qualified technical review. For commercial selection, the compound name should be considered separately from the specification and supplied form required for the intended process.

Technical profile

Product properties

Review the product identity and general physical profile before specifying the grade required for your operation.

IUPAC name
propan-2-ylidenehydrazine
Category
Organic nitrogen compounds
Subcategory
Ketone hydrazones
Molecular formula
C3H8N2
Molecular weight
72.11 g/mol

Uses and markets

Applications and industries

The correct product specification depends on the intended process, grade requirements and operating conditions.

Detailed product information

Detailed 2-Propanone, hydrazone product information

Chemical reactivity and hydrazone formation

2-Propanone, hydrazone contains the characteristic C=N–N framework produced when propanone reacts with hydrazine under condensation conditions. The transformation replaces the carbonyl oxygen environment with a hydrazone linkage, creating a compound whose nitrogen atoms can influence electron distribution, protonation behaviour, and subsequent reactions. Reaction conditions determine conversion and may also affect hydrolysis or the composition of the final reaction mixture.

Compared with acetone itself, 2-Propanone, hydrazone is less representative of a simple ketone and more useful when nitrogen-directed reactivity is wanted. Compared with larger, substituted ketone hydrazones, its compact structure provides a less sterically demanding system for studying fundamental behaviour. These comparisons describe chemical relationships, not a guarantee that one compound can replace another in a particular synthesis or analytical method.

Use in synthesis and analytical studies

In organic synthesis, 2-Propanone, hydrazone may be selected as a propanone-derived building block or as a substrate for transformations involving hydrazone nitrogen. The exact role depends on the reaction partner, catalyst, solvent, temperature, and work-up. Researchers commonly consider whether the hydrazone is intended to remain intact, undergo cleavage, or direct a later conversion, because those objectives require different reaction designs.

For analytical work, 2-Propanone, hydrazone can provide a defined reference substance or reaction component when laboratories investigate carbonyl chemistry. Identification may involve a combination of chromatographic, spectroscopic, and other laboratory techniques selected for the matrix and purpose. A method developed for acetone, hydrazine, or another hydrazone should not automatically be assumed to transfer without compound-specific evaluation.

Formulation and compatibility considerations

The behaviour of 2-Propanone, hydrazone is influenced by the medium surrounding it. Acidic conditions may alter nitrogen protonation, while water and reaction conditions may promote cleavage of the hydrazone linkage. Solvent selection can therefore affect dissolution, reaction rate, analytical response, and apparent stability. Users should evaluate the complete formulation rather than infer performance from molecular formula or molecular weight alone.

Acetone hydrazone can be compared with benzaldehyde hydrazone or other aromatic hydrazones to illustrate how substitution changes steric environment, conjugation, and physical behaviour. Those compounds may show different spectral characteristics and reaction pathways. Consequently, a related hydrazone can support method development or mechanistic comparison, but it is not necessarily an interchangeable substitute for 2-Propanone, hydrazone in a validated procedure.

Technical evaluation for laboratory use

When evaluating 2-Propanone, hydrazone, laboratories should define the intended chemical question before selecting a preparation or method. Useful considerations include reaction stoichiometry, possible residual propanone or hydrazine, moisture sensitivity, matrix effects, and the detection response expected from the hydrazone. These factors are especially relevant when a condensation reaction is being monitored rather than merely identifying an isolated compound.

The compound’s relatively small molecular structure distinguishes it from more elaborate hydrazones used as chromophoric or multifunctional intermediates. That distinction can affect separation, signal intensity, and downstream derivatization strategy. Technical conclusions should therefore be based on compound-specific experiments and suitable controls, with attention to the actual solvent, concentration, temperature, and reaction duration used in the intended application.

Frequently asked questions

Questions about 2-Propanone, hydrazone

How is 2-Propanone, hydrazone formed from propanone?

2-Propanone, hydrazone is formed through a condensation reaction between propanone and hydrazine. The carbonyl group of propanone reacts with the hydrazine nitrogen, and the process involves loss of water as the C=N–N framework develops. Reaction rate and conversion depend on factors such as acidity, solvent, temperature, water content, and stoichiometric balance. The resulting hydrazone is not simply a mixture of propanone and hydrazine; it is a distinct nitrogen-containing compound. In practical work, the reaction mixture may also contain unreacted starting materials, water, or side products, so isolation and analytical confirmation require a method suited to the actual conditions used.

What chemical feature defines 2-Propanone, hydrazone?

The defining feature of 2-Propanone, hydrazone is its hydrazone linkage, commonly represented as a carbon–nitrogen double bond connected to an amino nitrogen. This structure originates from the propanone carbonyl group and gives the compound reactivity different from that of the starting ketone. The two nitrogen atoms influence polarity, protonation, and possible reactions with electrophiles or under hydrolytic conditions. The molecule is compact, with formula C3H8N2, but its small size does not eliminate the importance of solvent and reaction environment. Structural descriptions should be distinguished from assumptions about physical form, stability, or suitability in a particular formulation.

Can 2-Propanone, hydrazone hydrolyse?

Hydrazones can undergo hydrolysis under suitable conditions, and 2-Propanone, hydrazone should be evaluated with that possibility in mind. Water, acidity, temperature, reaction time, and the surrounding solvent system can all influence whether the C=N linkage remains intact. Hydrolysis may regenerate propanone and hydrazine-containing species, although the extent and rate depend on the specific environment. A dry or neutral system may behave differently from an aqueous acidic mixture. Users studying stability should monitor the compound and relevant transformation products with an appropriate analytical method rather than relying solely on visual appearance or a theoretical structure.

How does 2-Propanone, hydrazone differ from acetone?

Acetone is the common name for propanone, a ketone with a carbonyl group. 2-Propanone, hydrazone, also called acetone hydrazone, is the condensation derivative formed when that carbonyl functionality reacts with hydrazine. The structural change replaces the ketone’s oxygen-centred reactivity with a nitrogen-containing hydrazone linkage. As a result, the compounds can differ in polarity, protonation, analytical response, and reactions with other substances. Acetone may be used as a starting material in preparing the hydrazone, but it is not an equivalent substitute in a procedure that requires 2-Propanone, hydrazone or a defined C=N–N functionality.

What is 2-Propanone, hydrazone used for in research?

2-Propanone, hydrazone is used in selected research settings as a compact model hydrazone, a propanone-derived synthetic intermediate, or a compound for examining carbonyl-to-hydrazone chemistry. Researchers may study its formation, hydrolysis, nitrogen reactivity, reaction mechanisms, or behaviour in analytical systems. It can also be considered when developing transformations that require a small hydrazone substrate. The exact use depends on the experimental design, solvent, reagents, and desired outcome. A research application should not be treated as proof of suitability for manufacturing, pharmaceutical, food, or other regulated purposes without separate compound-specific assessment. The final decision should consider the supplied 2-Propanone, hydrazone specification, intended process and applicable requirements rather than the chemical name alone.

What should be considered when analysing 2-Propanone, hydrazone?

Analysis of 2-Propanone, hydrazone should account for its possible reaction with water, acid, and other matrix components. The chosen method should distinguish the intact hydrazone from propanone, hydrazine-derived species, and any products formed during sample preparation. Chromatographic or spectroscopic techniques may be appropriate, but the best approach depends on concentration, solvent, matrix, and the analytical question. Calibration behaviour, recovery, detection response, and solution stability should be assessed during method development. A procedure designed for another hydrazone or for propanone should not automatically be considered suitable without compound-specific comparison and experimental confirmation.

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